Starting Patients on SPRAVATO®

Refer a Patient

Below, find resources and information on the 3 steps to start your appropriate patients on SPRAVATO® at a REMS-certified treatment center.

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Find a SPRAVATO® treatment center

Establish a relationship with local treatment centers

  • Use the Find a Center tool on spravatohcp.com to find a local REMS-certified treatment center that accepts your patient's insurance

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    Pro Tip: When using the Find a Center tool, you can filter by insurance plans

  • Connect with the treatment center to understand their referral process, and confirm if the treatment center is accepting new patients for SPRAVATO®
  • Understand the treatment center’s logistics, including what days of the week they offer SPRAVATO® and other amenities (such as extended hours)
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HCP talking to treatment center

Submit the referral directly to the treatment center

Refer your patients

  • You do not have to complete the benefits investigation or prior authorization to get your patients started
  • Provide all patient information so the treatment center can complete the benefits investigation and prior authorization, including:

    Insurance information

    Medication history

    Past treatment failures

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    Pro Tip: Based on the insurance plan, your patient may have 2 insurance cards, one each for pharmacy and/or medical benefits

  • The treatment center you refer to may have a referral process in place. If not, consider using the Patient Referral for SPRAVATO® Treatment Form to fax the needed information
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HCP providing care to their adult SPRAVATO® (esketamine) patient

Continue to provide care for your patient

Continue to provide care to your patients

You can be confident that your patients are supported throughout their treatment experience with SPRAVATO® when you:

  • Continue follow-up and ongoing appointments with your patient as appropriate
  • Ask your patient about their progress on SPRAVATO®
  • Stay connected with the treatment center to receive progress updates on your patient

SPRAVATO® Referral Guide

Download the full referral guide for more information on referring your patient to a SPRAVATO® REMS-certified treatment center.

SPRAVATO® Referral Form

Download the Patient Referral Form for SPRAVATO® treatment to enable communication between referring physician, treatment center, and patient.

Find a Treatment Center

Locate a certified SPRAVATO® treatment center

Calling and providing patient information to the treatment center ahead of time may help ensure timely coordination of care and a more seamless experience for your appropriate patients. Once you’ve decided SPRAVATO® may be an option for your adult patients with TRD, help them locate a certified SPRAVATO® treatment center.

Find a SPRAVATO® (esketamine) nasal spray Near You
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Become a Treatment Center

Becoming a REMS-certified SPRAVATO® treatment center

Learn more from physicians currently treating adult patients with TRD in certified treatment centers.

These healthcare providers have been compensated by Janssen Pharmaceuticals, Inc., for their participation in the video.

For practices interested in becoming a certified SPRAVATO® treatment center, consider the following:

  • Treatment centers must comply with full SPRAVATO® REMS requirements. For full REMS requirements, visit SPRAVATOrems.com or call 855-382-6022
  • SPRAVATO® is a Schedule III controlled substance
    • Treatment center protocols should be followed for handling Schedule III products in accordance with federal, state, and local regulations
  • SPRAVATO® treatment requires the ability and capacity for scheduling frequent appointments
  • SPRAVATO® treatment requires staff and equipment to provide appropriate patient monitoring
REMS= Risk Evaluation and Mitigation Strategy.