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SPRAVATO® REMS Certification | SPRAVATO® (esketamine) HCP

SPRAVATO® REMS Certification

While becoming REMS certified is a multistep process, information you need to complete the certification process can be found below and on the official SPRAVATO® REMS website.

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Scroll down to learn more about the SPRAVATO® REMS certification process and visit the SPRAVATO® REMS website for more information.

REMS=Risk Evaluation and Mitigation Strategy.

Completing the SPRAVATO® REMS Certification

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How does your outpatient treatment center become certified in the SPRAVATO® REMS?

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Designate an Authorized Representative to oversee implementation and coordinate the activities of the SPRAVATO® REMS

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Review the following materials:

  • SPRAVATO® Prescribing Information
  • SPRAVATO® REMS Program Overview
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Have the Authorized Representative complete and submit the Outpatient Healthcare Setting Enrollment Form at, or complete the paper form and fax to the SPRAVATO® REMS at 1-877-778-0091

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Once submitted, you will be notified of certification in the SPRAVATO® REMS and you will receive information on additional requirements necessary to order and receive SPRAVATO®

To review all SPRAVATO® REMS Outpatient Healthcare Setting requirements, see the Outpatient Healthcare Setting Enrollment Form on the SPRAVATO® REMS website.

REMS=Risk Evaluation and Mitigation Strategy.

What to Know About Becoming a REMS-Certified SPRAVATO® Treatment Center

Watch the video below for an overview of considerations before setting up a REMS-certified SPRAVATO® treatment center.

REMS=Risk Evaluation and Mitigation Strategy.