The first and only NMDA receptor antagonist approved in conjunction with an oral AD for TRD in adults1

SPRAVATO® hypothesized mechanism of action

When administered in conjunction with an oral antidepressant,

SPRAVATO® demonstrated efficacy in treatment-resistant depression in adults1

Superior improvement in depression symptoms at Week 41

Short-term efficacy

Significantly delayed time to relapse in a long-term study1

Long-term efficacy

SPRAVATO® demonstrated safety in short- and long-term studies1

The most commonly observed 
adverse reactions*
  • Dissociation
  • Dizziness
  • Nausea
  • Sedation
  • Vertigo
  • Hypoesthesia
  • Anxiety
  • Lethargy
  • Blood pressure increased
  • Vomiting
  • Feeling drunk

*Incidence ≥5% and at least twice that of placebo plus oral antidepressant.

SPRAVATO® does not require daily dosing

SPRAVATO® should be administered in conjunction with an oral antidepressant1

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Janssen CarePath

Your one source for Access, Affordability, and Treatment Support for your patients

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Find a Certified SPRAVATO® Treatment Center

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Become a Certified SPRAVATO® Treatment Center

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Reference

1. SPRAVATO® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc. February 2020.